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Factors associated with delayed infant immunization in a nationally representative cohort study

24 Jun, 2018
J. Homel, B. Edwards, Source: Child: Care,health and development

bstract

Background

Many children in developed countries do not receive recommended vaccines on time. However, knowledge about factors related to timeliness remains limited. Quantifying the relative impact of parental attitudes compared with socio‐demographic factors for delayed immunization would inform policy responses.

Methods

Participants in the nationally representative Longitudinal Study of Australian Children were matched with their vaccination histories in the Australian Childhood Immunisation Register (N = 4,121). Information about the children and their families were collected in face‐to‐face interviews in 2003–2004. We considered whether children had completed the primary course for each recommended antigen due by 6 months old. Children were categorized as either fully immunized, delayed, or totally non‐immunized. The outcome was examined using logistic regression. Population attributable fractions were estimated for key predictors.

Results

Delayed immunization was significantly associated with indicators of social disadvantage as well as parental disagreement with immunization. Attributable fractions for delayed immunization included lone motherhood (3.8%; 95% confidence interval CI [0.8, 6.7]), larger family size (39.5%; 95% CI [31.2, 46.8]), residential mobility (3.3%; 95% CI [0.1, 6.5]), lack of private hospital insurance (9.4%; 95% CI [0.7, 17.3]), a medical condition in the child (2.0%; 95% CI [0.2, 3.9]), and parental disagreement with immunization (2.1%; 95% CI [0.3, 3.9]).

Conclusions

Parental attitudes accounted for a relatively small percentage of delayed infant immunization. In contrast, many children who did not receive vaccines on time were characterized by social disadvantage, especially larger family size. Researchers and policy‐makers should consider how to make timely immunization easier for busy parents.

This entry was posted on Sunday, June 24th, 2018 at 10:11 am and is filed under Literature.

Literature Literature archive

S Krishnaswamy, P Lambach, ML Giles 2019 HUMAN VACCINES & IMMUNOTHERAPEUTICS VOL. 15, NO. 4, 942–950
Editorial 2019 Lancet Adolescent Health Vol 3: 281
AHviid, JVinsløv Hansen, M Frisch,, et al 2019 Ann Intern Med 170(8):513-520.

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