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Mistrust in Medicine: The Rise and Fall of America’s First Vaccine Institute

13 May, 2018
T Lanzarotta and MA Ramos., Source: AJPH

In 1813, the American government passed An Act to Encourage Vaccination, the first federal endorsement of a medical practice in American history. The law tasked a federal agent with maintaining a supply of the smallpox vaccine and distributing it nationwide. James Smith, a well-respected physician and proponent of vaccination, was appointed as vaccine agent. Smith was skeptical of claims that only well-trained physicians should be allowed to perform vaccination; he felt it was a simple procedure that should be available to all American citizens. In 1822, he made a tragic error that caused several deaths and left him vulnerable to criticism from political opponents and his medical peers. This ended Smith’s professional career and led to the repeal of the act itself. In this article, we use the rise and fall of James Smith to provide a historical perspective on contemporary debates surrounding delayed vaccination schedules. We explain how physicians—in the 19th century and today—have worked to build public trust in vaccination in an American culture suspicious of medical expertise.

This entry was posted on Sunday, May 13th, 2018 at 11:55 am and is filed under Literature.

Literature Literature archive

S Krishnaswamy, P Lambach, ML Giles 2019 HUMAN VACCINES & IMMUNOTHERAPEUTICS VOL. 15, NO. 4, 942–950
Editorial 2019 Lancet Adolescent Health Vol 3: 281
AHviid, JVinsløv Hansen, M Frisch,, et al 2019 Ann Intern Med 170(8):513-520.

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